In Model I, when plasma drug concentrations are high (., C p ≫I C 50 ), I C 50 becomes insignificant and the C p values cancel out, and if I max = 1, then I( t ) = 0. At high drug concentrations k in o times zero is zero; thus, there is complete blockage of the production of the response variable. Later, when plasma concentrations decline to low values, C p would be below I C 50 ( C p ≪I C 50 ). When that happens, drug effect would be zero and I( t )=1, meaning k in o would be back to its full value. The system returns toward its baseline as k in o will be refilling the pharmacodynamic compartment with the response variable.
The most recommended oral steroids cycle is the one, which consists of a single product. This way the possible effect on the state of the liver would be lessen. There are no rigidly defined framework of the oral steroids course duration, so it is better to consult with the experts, before starting the course. The daily amount of the steroid may vary. Therefore, before you are going to take steroids for muscle gaining in tablet form, make sure you have read the application note of the medicine. Most of coaches maintain that the oral steroids and the injectable steroids could be taken simultaneously only when using a certain system.