Seventeen male physical education students performed three types of treadmill exercise: (1) progressive exercise to exhaustion, (2) prolonged exercise of 50 min duration at the anaerobic threshold of 4 mmol . l-1 blood lactate (AE), (3) a single bout of short-term high-intensity exercise at 156% of maximal exercise capacity in the progressive test, leading to exhaustion within min (ANE). Immediately before and after ANE and before, during, and after AE adrenaline, noradrenaline, growth hormone, cortisol, insulin, testosterone, and oestradiol were determined in venous blood, and glucose and lactate were determined in arterialized blood from the earlobe. Adrenaline and noradrenaline increased 15 fold during ANE and 3--4 fold and 6--9 fold respectively during AE. The adrenaline/noradrenaline ratio was 1 : 3 during ANE and 1 : 10 during AE. Cortisol increased by 35% in ANE (12% of which appeared in the postexercise period) and 54% in AE. Insulin increased during ANE but decreased during AE. Testosterone and oestradiol increased by 14% and 16% during ANE and by 22% and 28% during AE. The results point to a markedly higher emotional stress and higher sympatho-adrenal activity in anaerobic exercise. Growth hormone and cortisol appear to be the more affected by intense prolonged exercise. Taking plasma volume changes and changes of metabolic clearance rates into consideration, neither of the exercise tests appeared to affect secretion of testosterone and oestradiol.
Thank you for reaching out and asking your question. MAO SNPs are a fascinating part of our physiology, and genes like these can influence how we feel and act on a profound level. People with MAO-A actually have a SLOWED breakdown of serotonin/dopamine. The feeling of anxiety is often a result of high dopamine (catecholamines) and/or serotonin. If your daughter takes a supplement, any supplement, and you see a flaring in her anxiety symptoms, then it means she is taking the wrong supplement. You need to find out why she has elevated neurotransmitters in the first place. In other words, what is the source of stress that is activating her fight or flight system? Trying to support ONE gene with ONE supplement gets complicated very quickly. A better idea is to look at the totality of the person, in this case your daughter, and find the areas where her system is weakest. By looking at things holistically we can find areas of her body that aren’t working well which are contributing to her symptoms. Remember, the environment controls the genes. We can’t change our genes, but we can change the environment. If you would like my personal help in figuring out how to support your daughter’s genetics, then I invite you to contact my office for a new patient consultation. We can be reached at 208-322-7755 and redmountainclinic@ . Treating genes is really about treating the whole person. When you do that, you optimize lives and optimize genes!