Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen , estrogen , or mineralocorticoid receptors , thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (. mast cell , eosinophil , neutrophil , macrophages , and lymphocytes ) and mediators (. histamine , eicosanoids , leukotrienes , and cytokines ) involved in inflammation . Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability .
Though they each try to get your symptoms under control, they do it by different mechanisms which when taken altogether, can work even better than by itself.
So, using the table below, a patient can generally take one medication from each column at the same time (but not more than one medication contained within a column unless directed by your doctor). For example (highlighted in BOLD ), a patient can choose to take allegra, nasonex, singulair, patanase, nasalcrom, and saline flushes all at the same time.
Steroid Nasal Spray
Anti-Histamine Nasal Spray
Cromolyn Nasal Spray