There is variation in the literature with regard to dosage regimens. Prednisone mg/kg/day to 1 mg/kg/day PO is commonly reported, followed by gradual taper over 3 to 6 weeks. Use of IV methylprednisolone for a few days may precede oral corticosteroid use. NOTE: Following biopsy to confirm diagnosis, corticosteroids are usually instituted soon afterward as an adjunctive measure; removal of the suspected offending agent /cause is the primary treatment. While many case reports suggest a possible net benefit to the use of corticosteroids, some experts advocate for more prospective study of their value.
4years ago I had which I now know was PMR. Although never diagnosed at that time I was treated with tapering doses of prednisone and analgesic meds and after 6 mos all symptoms disappeared. Three months ago after a mild URI I came down with the EXACT same symptoms a frustrating condition! Only abnormal tests were very high sed rate and C-reactive proteins which are indicative of edema,along with a mild anemia. Went back to the same Drs who were perplexed as to why I had this 4 year remission until I went to a new Rheumatologist ( previous one had retired) who finally diagnosed PMR. 24 hours after the first dose of steroid(40mg) I was 85% better. I am now on a tapering dose currently 20mg and take acetaminophen at regular 4 hour intervals( being. Careful not to exceed 4000mg max per day )
It has given me my life back. I am being followed for side effects of the steroids but the plan is to keep tapering dosage till weaned completely. I know this is not a cure but if it will give me another 4 year respite I will be eternally grateful! (I am now 62yr but first episode was at age 58)