Overall, 51 patients with isolated vulvar and/or perianal genital warts were included. Of those patients, 11 (%) had acuminate and 40 (%) had papular genital warts. All the women had lesions of the labia minora. The other localizations were as follows: labia majora, 18 (%); lateral vulva, 5 (%); clitoris, 9 (%); fourchette, 16 (%); and perianal area, 7 (%). All lesions were successfully treated by the end of the treatment period (median, 4; range 2-5). None of the patients had recurrence or new lesions during the 6-month follow-up period. In the second 6 months, 9 patients (%) were diagnosed with recurrent lesions. Although all the patients experienced transient burning pain during therapy, none of them discontinued the therapy. Ulceration was observed in 8 patients (%). Of those patients only 3 had permanent scarring (%).
Vulvar organs and tissues can become infected with different pathogens , or infested by parasites . Any inflammation caused is called vulvitis . Sexually transmitted infections may cause signs and symptoms on the vulva even though the agents may not be visible in the vulvar region. Vulvovaginal health measures can help to prevent many disorders.  Vaginitis can have many causes and different health measures can help its prevention . The following infections include those that can also be classed as sexually transmitted infections . Infections of the vagina such as vaginosis and of the uterus may produce vaginal discharge which can be an irritant when it comes into contact with the vulvar tissue, causing itching , inflammation and discomfort.   Bacterial infections include: Chancroid caused by Haemophilus ducreyi ; Granuloma inguinale caused by Klebsiella granulomatis ; Syphilis caused by Treponema pallidum ; and Gonorrhea caused by the bacterium Neisseria gonorrhoeae .