In this phase II dose-finding study, 54 patients with CKD stage 5 were randomized to either low, medium or high doses of ND (50, 100 or 200 mg/week for 24 weeks, respectively, in males; doses halved in females), while 7 patients acted as non-randomized controls. The primary outcome measure was appendicular lean mass (ALM) by dual-energy X-ray absorptiometry. Fluid overload (hydration of the fat-free mass) and indicators of physical functioning were secondary measures. Harms were also recorded. Data were analysed using Quade's (1967) non-parametric analysis of covariance.
The drug, although classified as an anabolic, however, androgenic side effects can occur. For example, perhaps increasing the oiliness of the skin, acne, hair growth on the body and face. Therefore, to avoid these unpleasant consequences, it should be strictly comply with the recommendations on the dosage of the drug. Women should be aware of the possible consequences virialization while taking the drug. In this case, they can have unpleasant phenomena such as voice. This coarse with low androgenic activity, androgenic side effects are much greater than threshold testosterone or fluoxymesterone methandrostenolone the. Do not forget that the drug can reduce the production of natural male libido and testosterone in the body. Reductase inhibitors should not be taken in the course nandrolone, as this may result in the exacerbation of side effects and impairment of general physical condition of the athlete.