Side effects/ Undesired effects/ Adverse drug reactions: Systemic steroid effects on higher doses. - / / / This entry was posted in Asthma Medications . Bookmark the permalink . ← Beclate-N Cream Beclo Lotion → 2 Responses to Beclate Nasal Spray / Beclate Aquanase Nasal Spray
The precise mechanism through which fluticasone propionate affects rhinitis symptoms is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (., histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation. In 7 trials in adults, fluticasone propionate nasal spray has decreased nasal mucosal eosinophils in 66% of patients (35% for placebo) and basophils in 39% of patients (28% for placebo). The direct relationship of these findings to long-term symptom relief is not known.